Cardiac causes of a raised JVP include:. The A wave is caused by the contraction of the right atrium, where blood is being pumped through the tricuspid valve into the right ventricle. Increased pressure in the right atrium also forces blood upwards towards and into the IJV. This influx of venous blood into the IJV is known as the A wave. The first part of the X descent is caused by relaxation of the right atrium , which results in blood filling the right atrium from the superior vena cava, reducing the height of the column of blood sitting in the IJV i.
The right ventricles relaxation also contributes to the X descent, as blood exits the right atrium into the right ventricle, further reducing the column of blood in the SVC and IJV.
The C wave is caused by the forceful contraction of the right ventricle which ejects blood out of the heart into the pulmonary artery. As this occurs, the pressure within the right ventricle increases significantly, forcing the tricuspid valve upwards so much so that it projects partially into the right atrium. This sudden projection of the tricuspid valve into the right atrium generates upwards force which is transmitted into the SVC and ultimately the IJV, causing a temporary rise in the JVP referred to as the C wave.
The second part of the X descent occurs during the final phase of right ventricular contraction. When the ventricle reaches its most contracted state, it is physically much smaller than when in its relaxed state, resulting in the creation of extra space within the pericardium.
This extra space within the pericardium allows the right atrium to expand and begin filling with blood. This initial phase of atrial filling results in a drop in venous pressure within the SVC and IVC, producing the second part of the X descent. The V wave is caused by the relaxation of the right atrium whilst the tricuspid valve is still closed.
The relaxation of the right atrium combined with a closed tricuspid valve results in blood being drawn into the column of blood that begins at the right atrium and extends up to the IJV. As blood is drawn into the column, whilst the tricuspid valve is closed, the level of the JVP is temporality increased. The Y descent occurs when the tricuspid valve opens, resulting in blood from the right atrium filling the right ventricle and blood from the SVC and IJV filling the right atrium.
This results in a decrease in the height of the column of blood and thus a decrease in the JVP. Clinical Examination. An Introduction to the Arclight. Eye Drops Overview. Prescribing in Renal Impairment. Interpreting Hepatitis B Serology. Medicine Flashcard Collection.
In future studies, a deeper exploration of the unique intricate venous anatomy should help understand the differences in JVP waveforms morphologies. Ultimately, a clinical validation study, to assess the neck contact PPG modality against invasive catheterization should be carried out to evaluate the viability of implementing our alternative in continuous CVDs monitoring. This work proposes, for the first time in literature, the use of reflectance contact PPG on the anterior neck, as a non-invasive, low cost alternative to sense JVP and obtain physiological parameters of relevance for CVDs.
Data acquisition from a total of 20 participants provided a snapshot of the pressure variations occurring at the right atrium of the heart, as reference ultrasound measurements of the internal jugular vein validated. To demonstrate the hypothesis i. Calculation of time differences between significant features confirmed the validity of the novel JVP signals, their annotation, and the consistency with previous methods in the literature. In addition, the extracted average neck JVP waveforms highlighted some singularities of the presented technique.
Despite the fact that all distinctive a, c, v waves could be identified, some pulse shapes showed a more triangular contour than typical, as a result of the reduced prominence of the y descent following the v wave. These findings are of great significance for the future design of low cost, wearable PPG-based sensors to continuously monitor changes in central venous pressure. Thus, this will aid in both, the efficiency in diagnosis of CVDs, as well as their management; whilst also eliminating some of the risks of invasive alternatives.
All experiments in this work were performed in accordance with the Declaration of Helsinki. The subjects were asked to be in a lying down position, since it was hypothesized and confirmed that JVP pulsations could not be properly sensed if participants were seated This is due to the fact that when the body is lying down, the venous return does not have to counteract the effect of gravity to pump blood back to the heart from the lower extremities, and blood is pumped more easily to the head.
In fact, neck venous pressure is elevated, enhancing the pulsatility of the JVP pulse at the neck. One reflectance pulse oximeter sensor R, Nonin coupled to an OEM processing module Xpod, Nonin , was located on the anterior area of the neck. A transmission finger pulse oximeter Onyx II , Nonin with Bluetooth connectivity, was located on the index finger of the left hand, and used as the ground truth.
A PPG sensor connected to the polysomnography system and placed on the index finger of the right hand, was used to synchronize with the two Nonin PPG sensors. The mounted imaging system, that was used to visualize the underlying venous system of the anterior neck, consisted of a P IR sensitive lens surrounded by IR LEDs — nm to illuminate the tissue.
Figure 10 shows the experimental setup, with one of the subjects lying down in supine position on a bed with all the attached sensors and imaging system. The IR vein camera online acquisition and Nonin PPG sensors recordings could be visualized in real-time on the screen to verify the venous anatomy of the neck area. Signals were acquired for 60 seconds duration for each subject.
After data acquisition, ECG recordings were imported into the computer for processing. Experimental setup. Participant lying down with two transmission pulse oximeters on each hand and one reflectance PPG sensor on the neck.
ECG and PPG signals acquired in parallel with the polysomnography system were synchronized and processed after the data acquisition session was finished. A diagnostic ultrasound US system Sonix RP, Ultrasonix coupled with a linear transducer probe MHz was also used to obtain transverse B-mode images and videos of the internal jugular vein in order to validate our PPG-based jugular measurements.
Using the 3. The output 2D topographic graph of 6. For that, all the pixels inside the segmented jugular walls were summed and scaled in terms of distance cm. In order to extract the JVP from the anterior neck, the contact reflectance PPG sensor was placed at the middle inferior region.
The JVA drains into the subclavian vein or occasionally into the external jugular vein EJV , which directly joins the superior vena cava further down, and ultimately the right atrium of the heart, as shown in Fig.
This venous configuration connecting the neck jugular veins in almost a straight path with the right side of the heart, allows RA pressure changes to be easily transmitted to the AJVs and JVA, in the form of the JVP. Neck venous system anatomy. For this reason, experiments were carried out with participants lying down.
Blood then concentrates more in the central venous compartment as a result of being less influenced by the gravitational pull, and hence, the JVP can be better observed in the neck venous system.
Another key feature that makes the frontal neck suitable for reflectance contact PPG sensing is the absence of thick tissues preventing the penetration of light. Neither the sternocleidomastoid nor the platysma superficial muscle cover the central lower area along the midline. On the contrary, the AJVs appear exposed in front of the infrahyoid muscles, and accessible superficially as they pierce the investing fascia Moreover, the skin thickness of the anterior neck is narrower than for the anterior-lateral regions In addition, the inferior part, is the thinnest compared to the middle and superior neck regions.
These anatomical properties facilitate the light to easily reach the subcutaneous plexus. In order to measure the correlation in the time-frequency plane between the neck JVP and finger ground-truth PPG signals the magnitude-squared wavelet coherence was used.
It was computed using the analytic Morlet wavelet over logarithmic scales, with a default value of 12 voices per octave. For two signals x and y , it is defined as:. C x a , b and C y a , b refer to the continuous wavelet transforms of x and y at scales a and positions b. The magnitude-squared wavelet coherence values range from 0 to 1, i. The phase of the wavelet cross-spectrum values were also extracted to inspect the relative lag between the neck JVP and finger PPG signals. For each subject, signals segments of 5 seconds duration were selected.
JVP signals were manually annotated by marking the characteristic a, c, v waves, as well as the onset of each JVP pulse corresponding to the trough before each v wave.
Each JVP cycle i. This was done similarly to Lam Po Tang et al. Using the whole duration of the recording 60 s , average JVP pulse shapes were obtained for each subject. For that, the automatic algorithm previously presented in 17 , was applied to perform segmentation, alignment and averaging with a quality correction stage, of JVP pulses. The average waveforms were annotated, after being normalized in amplitude and in time by the average pulse duration , for inter-subjects comparison.
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A comprehensive examination of topographic thickness of skin in the human face. Aesthetic Surgery Journal 35 , — Download references. You can also search for this author in PubMed Google Scholar. All authors I. Reprints and Permissions. Pulsations obliterated by pressure above the clavicle. Pulsations not obliterated by pressure above the clavicle. Level of pulse wave decreased on inspiration; increased on expiration. No effects of respiration on pulse.
Usually two pulsations per systole x and y descents. One pulsation per systole.
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